Rohto Eye Drops Research

-Rediscovering the Power of Panthenol -

Panthenol, also known as provitamin B5, is an excellent ingredient that activates cell metabolism. Besides eye drops, it's used in many other products, including dry skin remedies, hair growth products, shampoos, and conditioners.
Although panthenol has long been included in eye drops, there have been very few studies that have investigated its detailed mechanism of action. Rohto Pharmaceutical conducted research on the mechanism of panthenol in order to apply it to the development of more effective formulations for improving eye strain in modern people.

The effects of panthenol on muscles

Eye strain caused by muscle stiffness

When we look at something far away or something close up, we adjust our focus by moving the muscles in our eyes. When we look at something close up, our eye muscles are tense, so if you keep looking at something close up, such as when working on a computer, these muscles can become stiff.
This is one of the reasons why your eyes get tired.

Rohto Pharmaceutical's New Discovery

Muscle movement requires energy called "ATP." Rohto Pharmaceutical has newly discovered the mechanism by which panthenol produces ATP!

Elucidation of the mechanism

The mechanism by which panthenol effectively relieves eye strain has been elucidated.

"The mechanism by which the ciliary muscle moves when looking at something close up."

The effect of panthenol on mucin, which protects mucous membranes.

Mucin refers to the sticky substance secreted from mucous membranes such as those in the stomach, intestines, and nose. Mucin protects these mucous membranes, which helps prevent various diseases. Mucin is also present in tears, acting like an adhesive to retain moisture in the eyes. Rohto Pharmaceutical has discovered that panthenol has the effect of increasing mucin in cells! Further research is expected.

The three-layered structure of tears
Tears consist of an oil layer, a water layer, and a mucin layer, and the stability of tears is maintained by keeping each of these layers in balance.
Diagram of the three-layered structure of tears