Rohto V5

Supports sleep quality *! Crocetin
Research report *Depth of sleep

Rohto Pharmaceutical has been conducting research focusing on five visual abilities, but this time, we have newly focused on "sleep."​

Did you know there's a connection between your eyes and sleep?
Lack of sleep is thought to affect visual function. For eye health...
Getting enough sleep is also important.

What is crocetin?

Crocetin has been reported to have the function of supporting good quality sleep (improving sleep quality *, reducing the number of times one wakes up during the night, and alleviating drowsiness and fatigue upon waking).

*Depth of sleep

Crocetin is a natural yellow pigment found in gardenia fruit and saffron. It is also found in several herbal medicines and has been used for health purposes for centuries.

Crocetin is a type of carotenoid, related to "beta-carotene" found in carrots. It has strong antioxidant properties and, compared to common carotenoids, has a smaller molecular weight, making it easily absorbed.
Furthermore, crocetin is a precious ingredient, as only 10g can be extracted from 7.5kg of gardenia fruit.

Rohto Pharmaceutical's eye supplement, Rohto V5 Eye & Sleep Double Care, a functional food product.

●[Notification Statement] This product contains lutein, zeaxanthin, and crocetin. Lutein and zeaxanthin have been reported to increase macular pigment in the retina, reduce blurriness and haze, improve the ability to see clearly (contrast sensitivity), and protect the eyes from light stimuli such as blue light. Crocetin has been reported to support good quality sleep (improve sleep quality (depth of sleep), reduce the number of awakenings during the night, and alleviate drowsiness and fatigue upon waking). *Vision refers to the ability to clearly distinguish shades of color and outlines of objects (contrast sensitivity), which tends to blur with age. ●Maintain a balanced diet based on staple foods, main dishes, and side dishes. ●Unlike Foods for Specified Health Uses, this product has not been evaluated by the government for its functionality and safety. Information on the scientific evidence submitted can be found on the Consumer Affairs Agency website. ●This product is not intended for the diagnosis, treatment, or prevention of disease.

The effects of crocetin

Effect01

Improving the depth of sleep

Clinical trial results

Studies have reported that crocetin intake significantly increases "delta power," a brainwave observed during deep sleep.

Effect02

Improving morning drowsiness

Changes in sleepiness upon waking

Studies have reported that crocetin intake significantly improves morning drowsiness.

Effect03

Improvement of fatigue upon waking

Changes in fatigue recovery upon waking

Studies have reported that crocetin intake significantly improves morning fatigue.

Adapted from: Complement. Ther. Med. 2018;41:47-51.
Participants: 24 healthy adult men and women who regularly experience dissatisfaction with their sleep.
Sample intake period: 2 weeks
Daily intake: 7.5 mg of crocetin
Reason for data selection: Results of clinical trials involving Japanese men and women from among the papers included in the research review.

For more information about crocetin, click here.

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