Let's start by looking at the structure of the skin.

Our skin consists of three layers, from the outside in: the epidermis, dermis, and subcutaneous tissue.
It consists of three parts.

And within the epidermis, the outermost layer is the "stratum corneum."
It varies depending on the body part, such as the palms of the hands or the soles of the feet.

Generally, the stratum corneum is only about 0.02 mm thick.
In fact, this very thin layer plays an important role in maintaining healthy skin.
It does. The stratum corneum prevents foreign substances such as bacteria from entering the body,

It helps to reduce irritation from contact with the skin.

Furthermore, in order to maintain skin moisture, moisture is drawn from within the skin.
Protect it from evaporation,
It helps to retain moisture effectively.

When you look at the stratum corneum of healthy skin under magnification, you can see that there is moisture and oil between the keratinocytes.
It's layered like a mille-feuille.

This is called a "lamellar structure."

This lamellar structure is maintained by "intercellular lipids" in the keratinocytes.

This substance has parts that are easily attracted to water and parts that are easily attracted to oil.
I have both.

In the stratum corneum of healthy skin, intercellular lipids are arranged in a regular pattern.
Furthermore, the water and oil layers overlap in multiple layers, and the moisture is retained, creating a powerful effect.
It acts as a barrier.

Intercellular lipids that fill the gaps between keratinocytes

Substances such as "ceramide," "cholesterol," and "fatty acids"
It is composed of.

These are combined in a perfect balance, with water and oil alternating
It creates a state of being piled up.

This helps to keep your skin well-hydrated.

Conversely, the inside of the stratum corneum of "scratchy, dry skin R" is
The regularity of the intercellular lipids in the stratum corneum is disrupted, and the lamellar structure is broken.

When this happens, the skin cannot retain moisture and becomes dry.

The barrier function that protects us from external stimuli will cease to work.

Maintaining a proper lamellar structure in the stratum corneum is essential for healthy skin.
This is very important.

When the barrier function breaks down, nerve fibers extend into the epidermis.

Therefore, the skin is prone to itching even with slight irritation.
It has become that way.

Changing the lamellar structure of the stratum corneum is important for maintaining healthy skin.
This is very important.