Approximately once a month, one egg is released from the ovary during ovulation. During menstruation, the hypothalamus in the brain sends a signal to the pituitary gland, which secretes follicle-stimulating hormone (FSH) to encourage the formation of mature follicles. The stimulated follicles develop and eventually secrete estrogen, a type of follicular hormone. This hormone causes the uterine lining to thicken.
When a follicle matures and produces enough estrogen, the pituitary gland releases luteinizing hormone, signaling the body to ovulate. The follicle's membrane then ruptures, releasing the egg from the ovary, resulting in ovulation.
The released egg is taken up by the fallopian tube, and if it encounters sperm, it is fertilized. The resulting embryo is then sent to the uterus, where the uterine lining has thickened, and implants. If the egg does not encounter sperm, the uterine lining, which had thickened to facilitate implantation of the embryo, sheds, and menstruation begins.
Even if a woman ovulates for 30 to 40 years, she will only ovulate a few hundred eggs in her lifetime. The vast majority of the remaining eggs will not be ovulated and will simply disappear.
Around the age of 50, the eggs prepared for ovulation become depleted, and ovulation and menstruation stop. This is menopause.